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Advancing Science for Global Health
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Global Health Reciprocal Innovation

two women talking on a bench The Global Health Reciprocal Innovation (RI) project, coordinated by Fogarty's Center for Global Health Studies (CGHS), seeks to highlight how health innovations that have been researched, developed and implemented in low- and middle-income countries (LMICs) can be adapted and adopted to address similar challenges in U.S. In partnership with other NIH Institutes, Centers and Offices (ICOs) and the RI research community, the project seeks to explore methods, frameworks, concepts, and case examples of reciprocal innovation that will advance this area of research.

For the purposes of this project, we use the following definition of reciprocal innovation developed at Indiana University, Center for Global Health: “Reciprocal Innovation is the bi-directional and iterative exchange of a technology, methodology, or process between at least two countries, one lower- or middle-income country and one high income country, to address a common health challenge and provide mutual benefit to both sides. Lessons learned are continually shared throughout the process to suit the needs and infrastructure of each country.”

2019 - 2020 Request for Information and Webinar

The Global Health Reciprocal Innovation project began in 2019 with an environmental scan, which included a Request for Information (RFI) from the scientific community for examples of RI research. We received 21 responses to the RFI and proceeded to interview several of the respondents.

In October 2020, harnessing data collected from the RFI and the interviews, CGHS partnered with the National Institute of Mental Health (NIMH) and the NIH Office of Behavioral and Social Sciences Research (OBSSR) to host a webinar on Transferring HIV and Stigma Reduction Interventions from LMICs to the U.S. Experts shared case examples of HIV interventions that were in various phases of being transferred from LMICs to the U.S., with a focus on lessons learned from the transfer of stigma reduction interventions. Presenters described frameworks for intervention transfers, and key barriers and facilitators to this type of research.

2021-2022 Scoping review and RI Workshop

In partnership with the NIH library and two fellows, Dr. Jepchirchir Kiplagat (AMPATH/Fogarty Fellow) and Dr. M.C. Sage Ishimwe, (NIH NIMHD-NIDDK Rwandan Health program fellow) CGHS is finalizing a scoping review of the literature describing reciprocal innovation in health, specifically reciprocal innovation involving interventions discovered in an LMIC and transferred to an HIC. We intend to host a workshop in Fall 2022, which will convene scientific experts, funders, and policy makers to highlight case examples, discuss the science, barriers, and opportunities in RI, and discuss how to advance research related to RI in the future.

As the COVID 19 pandemic has shown, encouraging cross-national partnerships to address global health challenges enhances and accelerates our ability to respond to current common global health issues, and better prepares us to face future global health challenges.

NIH Partners

The following NIH Institutes, Centers and Offices are partnering with Fogarty on the Global Health Reciprocal Innovation project:


Linda Kupfer, Ph.D.
Senior Scientist
Center for Global Health Studies
Fogarty Division of International Science Policy, Planning and Evaluation
Email: linda.kupfer@nih.gov

Arina Knowlton
Global Health Research and Policy Analyst
Center for Global Health Studies
Fogarty Division of International Science Policy, Planning and Evaluation
Email: arina.kadam@nih.gov

Updated August 17, 2022