Full Award: Improving infant hydrocephalus outcomes in Uganda: Predicting developmental outcomes and identifying patients at risk for early treatment failure after ETV/CPC

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Global Brain Disorders Research

Project Information in NIH RePORTER

Improving infant hydrocephalus outcomes in Uganda: Predicting developmental outcomes and identifying patients at risk for early treatment failure after ETV/CPC

Principal Institution

Boston Children's Hospital

Principal Investigator(s) (PI)

Lin, Pei-Yi; Warf, Benjamin Curtis

Project Contact Information

Email: Ivy.Lin@childrens.harvard.edu

Year(s) Awarded

2018-2023

Country

Uganda

Collaborators

CURE Children's Hospital Uganda

NIH Partners

NICHD

Project Description

Neonatal hydrocephalus is a major global health problem, with an estimated 400,000 new cases rising annually, half of which occur in sub-Saharan Africa. Hydrocephalus can be treated by surgery, but failure is a significant problem, even in the United States, but even more so in LMICs, where emergency access to neurosurgical care is often impossible. This project aims to reduce the burden of hydrocephalus around the world by developing novel tests for objective, quantitative assessment of a patient’s brain health during the disease and prediction of their response to treatment and long-term neurodevelopmental outcome.

Related World Regions / Countries

Sub-Saharan Africa