Developmental neurotoxicity and autism spectrum disorder
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Developmental neurotoxicity and autism spectrum disorder
Principal Institution
University of Medical Sciences, Ondo
Principal Investigator(s) (PI)
Ijomone, Omamuyovwi Meashack
Project Contact Information
Email:
ijomoneom@futa.edu.ng
Year(s) Awarded
2022-2027
Country
Nigeria
Collaborators
Federal University of Technology
Project Description
Increasing evidence associates exposure to environment toxicants such as heavy metals to negative neurological consequences; particularly, perinatal exposure to heavy metals is increasingly linked to neurodevelopmental disorders. This study aims to investigate morphological, behavioral, and molecular alterations caused by developmental exposure to heavy metals in relation to endpoints of autism spectrum disorders (ASD).
This project will provide novel translational information on the importance of inherent genetic differences and exogenous chemical perturbations of cellular processes as potential modifiers of metal-induced neurotoxicity and neurodevelopmental disorders such as ASD, thus, laying the groundwork for innovative therapeutic strategies against neurodevelopmental disorders.
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