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Delineating the kidney brain axis in children with severe malaria (KID-BRAIN)

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Emerging Global Leader

Project Information in NIH RePORTER

Delineating the kidney brain axis in children with severe malaria (KID-BRAIN)

Principal Institution

Makerere University

Principal Investigator(s) (PI)

Batte, Anthony

Project Contact Information

Email: chdc@chdc.mak.ac.ug

Year(s) Awarded

2023–2028

Country

Uganda

Project Description

The overall goal of this career award is to build Dr. Batte into an independently funded physician scientist improving the  survival of children with acute kidney injury (AKI) and identify interventions that will enable children to thrive.

This career development project will delineate the mechanisms of kidney-related brain injury in severe malaria by determining the extent that AKI phenotypes are associated with biosignatures of brain injury and recovery. Further, Dr. Batte will establish the extent that AKI and AKI phenotypes are associated with cerebral edema, and in addition define the association between neurobehavioral outcomes, brain injury biomarkers, and AKI phenotypes.

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