Investigating the role of altered lung microbiome in fueling Th17 mediated airway inflammation in COPD among HIV-infected individual
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
HIV-associated Noncommunicable Diseases Research at LMIC Institutions
Project Information in NIH RePORTER
Investigating the role of altered lung microbiome in fueling Th17 mediated airway inflammation in COPD among HIV-infected individual
Principal Institution
Makerere University
Principal Investigator(s) (PI)
Kayongo, Alex
Project Contact Information
Email:
alexkayongo@gmail.com
Year(s) Awarded
2022–2024
Country
Uganda
Project Description
In this project, we will determine the association between lung microbiome and immune responses (particularly Th17/Treg responses) in the back of the lungs (distal airways) of people living with HIV (PLWH) with chronic obstructive pulmonary disease (COPD) in a controlled Ugandan cohort using bronchoalveolar lavage (BAL). Also called bronchoalveolar washing, BAL is used to collect a sample from the lungs for testing.
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