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Immune profiling to detect viral hepatitis-related liver cancer in HIV-infected patients
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
HIV-associated Noncommunicable Diseases Research at LMIC Institutions
Project Information in NIH RePORTER
Immune profiling to detect viral hepatitis-related liver cancer in HIV-infected patients
Principal Institution
University of Minnesota
Principal Investigator(s) (PI)
Debes, Jose Daniel
Project Contact Information
Email:
debes003@umn.edu
Year(s) Awarded
2022–2024
Country
Regional - Latin America; Brazil
Project Description
HIV-infected individuals are at high risk for hepatocellular carcinoma (HCC), particularly early occurrence, due to frequent viral hepatitis co-infection. This project will hypothesize that immune-markers in blood related to the immune reaction of the body towards HCC can be used to identify HIV- infected individuals with early HCC. It will also aim to cross-sectionally and prospectively evaluate peripheral immune variations secondary to HCC in HIV-infected individuals as markers to predict early HCC development.
Related World Regions / Countries
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