Biomarker-Guided Evaluation of Glycated Testing Modalities for Dysglycemia among Persons Living with HIV (BEGET)
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
HIV-associated Noncommunicable Diseases Research at LMIC Institutions
Project Information in NIH RePORTER
Biomarker-Guided Evaluation of Glycated Testing Modalities for Dysglycemia among Persons Living with HIV (BEGET)
Principal Institution
University of Maryland Baltimore
Principal Investigator(s) (PI)
Jumare, Jibreel
Project Contact Information
Email:
jibreel.jumare@ihv.umaryland.edu
Year(s) Awarded
2023-2025
Country
Nigeria
Collaborators
University of Abuja Teaching Hospital
Project Description
The glycosylated hemoglobin (HbA1c) test is considered highly valuable for early detection of diabetes but is currently not recommended for use among people living with HIV (PLHIV) due to their lower hemoglobin levels. This study will identify appropriate HbA1c diagnostic thresholds for strata of hemoglobin and markers of inflammation, insulin resistance, and immuno-virologic status, in addition to evaluating an alternative glycated test, fructosamine, with no hemoglobin limitation. Findings will inform the development of guidelines for the optimal use of glycated testing tools among PLHIV and others with low hemoglobin in the general population.
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