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Teens on TB Treatment: Predicting Adherence Through Clinical Decision Analysis

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

International Research Scientist Development Award (IRSDA)

Project Information in NIH RePORTER

Teens on TB Treatment: Predicting Adherence Through Clinical Decision Analysis

Principal Institution

Rhode Island Hospital

Principal Investigator(s) (PI)

Chiang, Silvia Shinpei

Project Contact Information

Email: silvia_chiang@brown.edu

Year(s) Awarded

2017-2023

Country

Peru

Collaborators

Partners in Health (Socios en Salud)

Project Description

Adolescents, who comprise a significant portion of tuberculosis (TB) cases globally, have demonstrated poor TB treatment adherence—which has dire consequences not only for the patients themselves but also for individuals to whom they may transmit the infection. Despite this public health problem, no published studies have examined adolescent-specific predictors of adherence to TB therapy. The research—which will take place in Peru—aims to develop a clinical prediction rule to identify adolescents at risk of poor TB treatment adherence, thus paving the way for targeted interventions to mitigate modifiable risk factors.

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