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Brain Disorders in the Developing World: Research Across the Lifespan

Status: Future competition expected



  • The Low- and Middle-Income Country (LMIC) collaborator must be at an institution in a country defined by The World Bank as low income, lower-middle income or upper-middle income. See The World Bank Country and Lending Groups to identify countries with low- and middle-income economies.
  • R01 applicants must have had an R21 planning grant under the companion announcement, and must have documentation that a participating partner agrees to accept assignment of the application.
  • See full "Section III: Eligibility Information" in each Announcement for full details.

Program Overview

The Brain Disorders in the Developing World: Research Across the Lifespan program develops collaborative research and capacity building projects on brain disorders throughout life, relevant to low- and middle-income countries (LMICs). Grant recipients develop innovative, collaborative research programs that contribute to the long-term goal of building sustainable research capacity in nervous system function and impairment throughout life.

The first phase of a project consists of a two-year planning and development grant using the R21 grant mechanism, which provides support to organize, plan for, prepare and assemble an application for a more comprehensive R01 grant. The R01 grant involves collaboration between developed and developing country investigators, and incorporates research and capacity building. During the R21 award period grant recipients:

  • further define the type and area of research to be developed
  • conduct pilot studies
  • develop and solidify collaborative relationships and understandings with the partners in the developed and developing countries involved

Applicants provide a plan to assess and address current resources and needs so the proposed research and capacity building can be successfully carried out. Training and other capacity-building opportunities should be incorporated into the research application in the context of the proposed research.

  • Page Limits - New page limits have been in effect since January 2010. One page is allowed for specific aims. One page is allowed for the introduction in resubmission. More information available from NIH Peer Review Policies and Practices.
  • Research Strategy Section - Three sections of the current Research Plan (Background and Significance, Preliminary Studies/Progress Report, and Research Design and Methods) will be consolidated into a new single section within the Research Plan entitled "Research Strategy." The new Research Strategy section - a single PDF upload in the PHS 398 Research Plan Component of the SF 424 (R&R) - is subdivided into three parts: Significance, Innovation and Approach. The Approach subsection includes Preliminary Studies for New Applications and Progress Report for Renewal/Revision Applications. Page limits for the Research Strategy section are:
    • Six (6) for R21, including revised applications and new submissions
    • Twelve (12) for R01, including both revised applications and new submissions
  • Email Updates - Subscribe to the Brain Disorders in the Developing World ListServ to receive updates on this program and related issues. Send an email to Type in the body of the email "subscribe brain-FIC-L."


Programmatic Issues

Dr. Kathleen Michels
Program Director
Division of International Research and Training
Fogarty International Center
Building 31, Room B2C39
31 Center Drive MSC 2220
Bethesda, MD 20892-2220
Telephone: (301) 496-1653
FAX: (301) 402-0779

Grants Management

Farah Bader, M.P.H.
Public Health Analyst
Fogarty International Center
Building 31, Room B2C29
31 Center Drive MSC 2220
Bethesda, MD 20892-2220
Telephone: (301) 402-5011
Fax: (301) 594-1211

Last Updated: 4/28/2014 3:00 PM