Global Alliance for Chronic Diseases

NIH participates in the Global Alliance for Chronic Diseases (GACD), a collection of publicly funded research agencies that supports innovative research collaborations to address the prevention and treatment of chronic diseases in vulnerable populations.

View and filter GACD-supported projects.

Cancer | Scale Up | Mental Health | Lung Disease | Type 2 Diabetes | Hypertension

GACD Primary and Secondary Prevention of Cancer

The current GACD funding call focuses on implementation research proposals for the primary and secondary prevention of cancer in low- and middle-income countries (LMICs), and in populations facing conditions of vulnerability in high-income countries.

• NIH funding opportunity supporting this call for applications: Notice of Special Interest (NOSI): Dissemination and Implementation Science for Cancer Prevention and Control in Low Resource Environments (NOT-CA-20-025)
  Submit applications using one of the following NIH funding opportunity announcements (FOAs). Applies to application due dates from June 5, 2020 through May 8, 2022.
• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) (PAR-19-274)
• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) (PAR-19-275)
• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) (PAR-19-276)
• Calls for applications on cancer from GACD, including how to apply to GACD associate members.

GACD Scaling-up Evidence-based Interventions

GACD is focusing on scaling-up evidence-based interventions at the population level for the prevention or management of hypertension or diabetes.

• Expired request for applications from NIH: Late-Stage Implementation Research Addressing Hypertension in Low- and Middle-Income Countries: Scaling Up Proven-Effective Interventions (UG3/UH3 Clinical Trial Optional) (RFA-HL-20-005)

GACD Mental Health Research

GACD funding agencies are accepting implementation research proposals on child, adolescent and adult age onset mental disorders including, but not limited to, dementia, depression, schizophrenia, bipolar disorders, alcohol- and drug-use disorders, etc., in low- and middle-income countries and/or in vulnerable populations in high-income countries.

• Expired request for applications from the National Institute of Mental Health (NIMH) at NIH: Implementation Science for the Prevention and Treatment of Mental and/or Substance Use Disorders in Low- and Middle-income Countries (U01) (RFA-MH-17-650)

GACD Lung Disease Research

GACD member organizations will accept implementation research proposals to address lung diseases related to environmental exposures, including indoor and outdoor air pollution and tobacco. Eligibility and application deadlines will vary by organization, and details will be released over time by each organization.

• NIH-funded trial to assess benefits of clean cookstoves
  Nov / Dec 2016 Global Health Matters
• GACD tackles the global burden of lung diseases
  Global Alliance for Chronic Diseases news, September 27, 2016
• NIH funding announcement: Household Air Pollution (HAP) Health Outcomes Trial (UM1), expired Jan 20, 2016

GACD Type 2 Diabetes Research

GACD member organizations, including NIH, recently solicited applications on type 2 diabetes with a focus on improving the science around implementation of existing interventions. NIH applications were accepted through the trans-NIH Initiative on Dissemination and Implementation Science for February 2014 application due dates.

• Global Alliance for Chronic Diseases (GACD) members [including NIH] fund landmark research into prevention and treatment of type 2 diabetes
  Global Alliance for Chronic Diseases news, August 20, 2015
• NIH joins global effort to fund diabetes research
  Jan / Feb 2014 Global Health Matters

GACD Hypertension Research

GACD members chose hypertension as their first joint funding initiative. Grants were announced in June 2012.

• Global Alliance for Chronic Diseases partners publish hypertension findings
  Jan / Feb 2016 Global Health Matters
• Related journal article: Behaviour change strategies for reducing blood pressure-related disease burden: findings from a global implementation research programme
  Implementation Science, November 9, 2015

Updated January 4, 2021