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Full Award: MRSI and DKI Evaluation of HIV-1 Clade C Infection in the Whole Brain

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Global Brain Disorders Research

Project Information in NIH RePORTER

MRSI and DKI Evaluation of HIV-1 Clade C Infection in the Whole Brain

Principal Institution

University of Miami School of Medicine

Principal Investigator(s) (PI)

Govind, Varan; Kumar, Mahendra

Project Contact Information

Email: vgovind@med.miami.edu

Year(s) Awarded

2016-2023

Country

India

NIH Partners

NINDS

Project Description

Human immunodeficiency virus (HIV-1) infection has become a chronic illness after the introduction of combination antiretroviral therapy (cART). However, due to a limited permeability of most cARTs into the brain, HIV-1 infection continues to exert its adverse effects on the central nervous system leading to neurocognitive dysfunctions in a significant percentage of HIV-1 infected individuals. This project aims to characterize the impact of HIV-infection in the brain of individuals with HIV-1 clade C infection prevalent in India.

Related World Regions / Countries

South Asia