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Combatting AntiMicrobial Resistance in Africa Using Data Science (CAMRA)

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Data Science for Health Discovery and Innovation in Africa (DS-I Africa)

Project Information in NIH RePORTER

Combatting AntiMicrobial Resistance in Africa Using Data Science (CAMRA)

Principal Institution

Redeemer's University

Principal Investigator(s) (PI)

Happi, Christian T.; Fouts, Derrick E.; Obaro, Stephen

Project Contact Information

happic@run.edu.ng

Year(s) Awarded

2021-2026

Country

Nigeria; Rwanda

Collaborators

Case Western Reserve University; International Foundation Against Infectious Diseases in Nigeria; J. Craig Venter Institute; Rhode Island Hospital; University of Nebraska Medical Center. (See Project Description for additional collaborators.)

NIH Partners

OD/NIH; NIAID

Project Description

Bacterial infections are highly prevalent and contribute significantly to morbidity and mortality across all age-groups but because appropriate bacterial diagnostic services are non- existent or very limited, finding the true cause of most infections and the true spread of antimicrobial resistance (AMR) is a major challenge in Africa, where data is limited. This program has three goals:

  1. to comparatively study bacterial isolates to inform trends in AMR and dynamics of transmission
  2. to incorporate markers of serious bacterial infection and gene products from resistant bacteria to create a portable screening tool for clinical care and to explore the antimicrobial properties
  3. to explore the potential benefit of an aminoglycoside-antimicrobial peptide complex for enhanced therapeutic efficacy against multidrug resistant bacteria.

Additional Collaborators

University of Nebraska-Lincoln; University of Rwanda; Nigeria Center for Disease Control; University of Abuja: National Institute of Pharmaceutical Research and Development (NIPRD); Hemex Health; Nigerian Institute of Medical Research; Rwanda Biomedical Centre;

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