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					Multi-target approach to rational design of novel therapeutics for human African trypanosomiasis
				
	
				
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
				
						Funding Fogarty Program
					Emerging Global Leader
				
					
						Project Information in NIH RePORTER
						
							Multi-target approach to rational design of novel therapeutics for human African trypanosomiasis
						
					
						Principal Institution
						
							Ahmadu Bello University 
						
					
						Principal Investigator(s) (PI)
						
							Balogun, Emmanuel Oluwadare
						
					
						Project Contact Information
						Email: 
oluwadareus@yahoo.com
					
					
						Year(s) Awarded
						
							2021-2026
						
					
						Country
						
							Nigeria
						
					
						Collaborators
						
							Libraries of Small Molecule Repository of Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) 
University of California San Diego (UCSD)
						
					
					
						Project Description
						Human African trypanosomiasis causes an estimated loss  of 1.35 million disability-adjusted life years (DALY) annually, and 65 million people are at risk infection. In addition, the region records an annual loss of US$4.5 billion  resulting from millions of cattle, camels, and small ruminants being killed by animal trypanosomiasis. To alleviate such heavy burden created by this disease on Africa, this project is designed to find novel compounds that ablate energy production in the disease pathogens and kill them. The success of this project will generate new classes of safe and effective anti-trypanosoma drug candidates and contribute to the health and economic development of Africa.
		
					
							
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