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Metabolomic predictors of weight gain during pregnancy and the postpartum period in South African women living with HIV
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Metabolomic predictors of weight gain during pregnancy and the postpartum period in South African women living with HIV
Principal Institution
University of Cape Town
Principal Investigator(s) (PI)
Madlala, Hlengiwe
Project Contact Information
Email:
hlengiwe.madlala@uct.ac.za
Year(s) Awarded
2024-2029
Country
South Africa
Collaborators
Northwestern University
Project Description
Excessive gestational weight gain (GWG) and postpartum weight retention (PPWR) contribute to the onset of metabolic complications and related chronic comorbidities such as diabetes and cardiovascular disease in women living with HIV (WLHIV). This project will conduct targeted and untargeted metabolomics testing in urine specimens collected in the first trimester of pregnancy to identify early biomarkers of GWG and PPWR. The goal is to allow early interventions to minimize adverse weight outcomes thereby improving long-term metabolic health in WLHIV.
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