Characterizing the Cyclic-di-AMP Pathway in Clostridioides difficile
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Emerging Global Leader
Project Information in NIH RePORTER
Characterizing the Cyclic-di-AMP Pathway in Clostridioides difficile
Principal Institution
Mahidol University
Principal Investigator(s) (PI)
Phanchana, Matthew
Project Contact Information
Email:
Matthew.pha@mahidol.edu
Year(s) Awarded
2025-2030
Country
Thailand
Project Description
This project is public health relevant because it aims to dissect the c-di-AMP pathway in C. difficile and explore its potential as a novel therapeutic target. Better understanding of the pathway and identification of small molecules targeting it will open the new opportunity for future drug development for this pathogen and others to tackle the ever-growing issue of antimicrobial resistance, while providing advanced trainings and platform for me to become an independent researcher. Therefore, the project fulfils the NIH’s missions “to foster fundamental creative discoveries, innovative research strategies, and their applications as a basis for ultimately protecting and improving health” and “to develop, maintain, and renew scientific human and physical resources that will ensure the Nation's capability to prevent disease”.
Related World Regions / Countries