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The Role of Sex Steroid Hormones in CD4+ T Cell-Mediated Immune Responses to Tuberculosis

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Emerging Global Leader

Project Information in NIH RePORTER

The Role of Sex Steroid Hormones in CD4+ T Cell-Mediated Immune Responses to Tuberculosis

Principal Institution

University of Sciences, Techniques and Technologies of Bamako

Principal Investigator(s) (PI)

Dabitao, Djeneba

Project Contact Information

Email: ddabitao@icermali.org

Year(s) Awarded

2019–2024

Country

Mali

Collaborators

Northwestern University
Johns Hopkins University

Project Description

The incidence of active tuberculosis (TB) is higher in men than women around the world, suggesting that being male increases the risk of progressing to active TB. Gaining a better understanding of why men are more likely to develop active TB and/or why women are less likely to progress to active TB could provide us with innovative, new ways to treat and prevent TB.

The goal of this Global Emerging Leader award is to establish Djeneba Dabitao, PharmD, Ph.D., as a leading, independent investigator and future mentor in research focused on the role of sex differences in immune responses, disease susceptibility, and treatment outcomes of infectious diseases, particularly in tuberculosis (TB).

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