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Defining Campylobacter and Immune Response Related Determinants in the Pathogenesis of Guillain-Barré Syndrome Patients in Low-Income Countries

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Emerging Global Leader

Project Information in NIH RePORTER

Defining Campylobacter and Immune Response Related Determinants in the Pathogenesis of Guillain-Barré Syndrome Patients in Low-Income Countries

Principal Institution

International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b)

Principal Investigator(s) (PI)

Islam, Zhahirul

Project Contact Information

Email: zislam@icddrb.org

Year(s) Awarded

2019–2024

Country

Bangladesh

Collaborators

University of Texas Health Science Center Houston

NIH Partners

NINDS

Project Description

This research project will identify potential biomarkers, nutritional factors, and microbial strain differences (using high-throughput sequencing) associated with the response of intravenous immunoglobulin (IVIg) treatment, as well as the clinical course and outcome of Guillain-Barré syndrome (GBS) in low-income countries. The study will improve the understanding of IVIg treatment outcome and provide insight to guide the development of personalized medicine for patients with GBS. The project will involve extensive training activities and guidance from the mentors and training advisory group.

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