Development of a Mobile Health Personalized Physiologic Analytics Tool for Pediatric Patients with Sepsis
The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).
Funding Fogarty Program
Mobile Health (mHealth)
Project Information in NIH RePORTER
Development of a Mobile Health Personalized Physiologic Analytics Tool for Pediatric Patients with Sepsis
Principal Institution
Rhode Island Hospital
Principal Investigator(s) (PI)
Garbern, Stephanie Chow; Levine, Adam Carl
Project Contact Information
Email:
sgarbern@brown.edu
Year(s) Awarded
2021-2026
Country
Bangladesh
Collaborators
Dhaka Hospital of the International Centre for Diarrhoeal Disease Research
Project Description
Worldwide, sepsis is responsible for the majority of deaths in children each year with most of these deaths occurring in low and middle-income countries (LMICs), yet few clinical tools have been developed for identifying, monitoring, or managing children with sepsis in LMICs. The research will develop and validate a mobile health tool which links continuous physiologic data obtained remotely from a wearable device with a standard smartphone and machine learning approach known as personalized physiologic analytics to provide clinicians with accurate assessments of advanced stages of sepsis (severe sepsis, septic shock, multiple organ dysfunction syndrome), and risk of death in septic children without the need for laboratory diagnostics or expensive monitoring equipment. By enabling detection of subtle physiologic changes indicating clinical deterioration, these tools may allow clinicians to intervene earlier, better direct care, and allocate scarce resources, thereby reducing child morbidity and mortality from sepsis.
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