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Development of a Mobile Health Personalized Physiologic Analytics Tool for Pediatric Patients with Sepsis

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Mobile Health (mHealth)

Project Information in NIH RePORTER

Development of a Mobile Health Personalized Physiologic Analytics Tool for Pediatric Patients with Sepsis

Principal Institution

Rhode Island Hospital

Principal Investigator(s) (PI)

Levine, Adam Carl

Project Contact Information

Email: alevine1@lifespan.org

Year(s) Awarded

2021-2026

Country

Bangladesh

Collaborators

Dhaka Hospital of the International Centre for Diarrhoeal Disease Research

Project Description

Worldwide, sepsis is responsible for the majority of deaths in children each year with most of these deaths occurring in low and middle-income countries (LMICs), yet few clinical tools have been developed for identifying, monitoring, or managing children with sepsis in LMICs. The research will develop and validate a mobile health tool which links continuous physiologic data obtained remotely from a wearable device with a standard smartphone and machine learning approach known as personalized physiologic analytics to provide clinicians with accurate assessments of advanced stages of sepsis (severe sepsis, septic shock, multiple organ dysfunction syndrome), and risk of death in septic children without the need for laboratory diagnostics or expensive monitoring equipment. By enabling detection of subtle physiologic changes indicating clinical deterioration, these tools may allow clinicians to intervene earlier, better direct care, and allocate scarce resources, thereby reducing child morbidity and mortality from sepsis.

Related World Regions / Countries

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