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Ebola virus disease (EVD) news, resources and funding for global health researchers
Ebola hemorrhagic fever is an acute viral disease that often leads to severe illness and death in humans and other primates. The infection typically affects multiple organs in the body and is often accompanied by hemorrhage. Once the virus has been transmitted from an animal host to a human, it can then spread through person-to-person contact.
Scientists employed and funded by NIH's National Institute of Allergy and Infectious Diseases (NIAID) have been working for decades to develop tests to diagnose Ebola virus early, therapies to treat illness caused by the virus, and vaccines to prevent infection. Because of the past outbreaks in West Africa,
NIAID's Vaccine Research Center is supporting the
development and testing of investigational vaccines. NIAID is also researching the
long-term health effects of Ebola on survivors.
Fogarty is supporting grants to plan
research training and capacity building programs focused on emerging viral epidemics in collaboration with institutions in Guinea, Liberia and Sierra Leone.
Updated January 2021
Top News
-
An Ebola therapy two decades in the making
NIH researcher Dr Nancy Sullivan led development of cutting-edge treatment
NIH Intramural Research Program blog post, February 10, 2021 -
FDA approves treatment [evaluated in a clinical trial led by NIH, DRC’s Institut National de Recherche Biomédicale] for Ebola virus
FDA news, December 21, 2020 -
Reston Ebolavirus spreads efficiently in pigs, finding reveals potential for spread to humans
NIAID/NIH news, December 21, 2020 -
Ebola: Then, Now and the NIH [Video]
NIH Demystifying Medicine Lecture
Recorded January 14, 2020 -
Investigational drugs reduce risk of death from Ebola Virus Disease
NIAID/NIH news, November 27, 2019 -
Candidate Ebola vaccine still effective when highly diluted, macaque study finds
Scientists hope findings mean vaccine supplies could stretch farther
NIAID/NIH media advisory, October 18, 2019 -
Ebola in Zaire, 1976: The Past as Prologue [Video]
featuring Fogarty senior scientist emeritus Dr. Joel Breman
CDC, September 5, 2019 -
NIAID’s ongoing Ebola efforts in Congo, elsewhere
NIAID Funding News, September 05, 2019 -
Independent monitoring board recommends early termination of Ebola therapeutics trial in DRC because of favorable results with two of four candidates
NIAID/NIH news, August 12, 2019 -
Investigational monoclonal antibody to treat Ebola is safe in adults
NIAID/NIH news, January 25, 2019 -
Clinical trial of investigational Ebola treatments begins in the Democratic Republic of the Congo
NIAID/NIH news, November 27, 2018 -
Experts highlight Ebola vaccine progress and suggest next steps
NIAID/NIH news, August 13, 2018 -
Scientists find strong immune cell responses in Ebola survivors
NIAID Now blog, August 9, 2018 -
Broadly acting antibodies found in plasma of Ebola survivors
NIAID/NIH news, July 17, 2018 -
NIAID responds to Ebola outbreak in the Democratic Republic of the Congo
NIAID Now blog, June 25, 2018 -
NIH begins testing Ebola treatment in early-stage trial
NIAID/NIH news, May 23, 2018 -
Despite mutations in Makona Ebola virus, disease consistent in mice, monkeys
NIAID news, May 8, 2018 -
Ebola virus infects reproductive organs in monkeys
NIAID/NIH news, February 8, 2018
Top Resources
NIH News and Resources
- Recorded webcast:
Antibodies Against Ebola and Lassa: A Global Collaboration [Video]
by Erica Ollmann Saphire, Ph.D.
Kinyoun Memorial Lecture from NIAID, December 5, 2017 -
Fogarty funds additional grants to support research training in Ebola-affected countries
Sep / Oct 2017
Global Health Matters - Report:
Integrating Clinical Research into Epidemic Response: The Ebola Experience
The National Academies Press, April 12, 2017 -
Fogarty protects Americans by building pandemic response capacity in Ebola-hit West Africa
Mar / Apr 2017
Global Health Matters -
Profile: Fogarty Fellow Dr Gilberte Bastien tackles Ebola's unseen mental scars in Liberia
Mar / Apr 2017
Global Health Matters -
Disease ‘superspreaders’ accounted for nearly two-thirds of Ebola cases, study finds
Washington Post, February 13, 2017 -
Fogarty provides support to Ebola-affected countries
Nov / Dec 2016
Global Health Matters -
Analysis of 1976 Ebola outbreak holds lessons relevant today
Fogarty news, June 29, 2016 -
Ebola, Zika modelers aim to inform policy decisions
Mar / Apr 2016
Global Health Matters -
PAHO's Dr Marcos Espinal on global partnerships to fight Zika, Ebola and other diseases
Mar / Apr 2016
Global Health Matters -
Commission considers how to improve global disease outbreak response
Mar / Apr 2016
Global Health Matters -
Experimental Ebola antibody protects monkeys: Antibody isolated from Ebola survivor can advance to clinical trials
NIAID/NIH news, February 25, 2016 -
Ebola survivor study yields insights on complications of disease: Other findings may have implications for potential sexual transmission of Ebola
NIAID/NIH news, February 23, 2016 -
NIH experts offer lessons learned from the 2014-2015 Ebola outbreak
NIAID/NIH news, January 14, 2016 -
The U.S. response to Ebola: Status of the FY2015 Emergency Ebola Appropriation
Kaiser Family Foundation, November 23, 2015 - Report:
Ebola R&D landscape of clinical candidates and trials
WHO, October 2015 -
Shining light on Ebola virus for faster diagnosis
Blog post by NIH Director Dr. Francis S. Collins, October 22, 2015 -
Medecins Sans Frontiere (Doctors Without Borders) receives Lasker-Bloomberg Public Service Award for leadership in responding to Ebola outbreak in Africa
Lasker Foundation news, September 8, 2015 -
NEI team in Liberia investigates ocular effects among Ebola survivors
NEI News Brief, September 8, 2015 -
Characterizing Ebola transmission patterns based on Internet news reports, co-authored by Fogarty staff scientist
Clinical Infectious Diseases, September 15, 2015 (published online September 3, 2015) -
Investigational aerosolized Ebola vaccine shows promise in nonhuman primates
NIAID/NIH news, July 13, 2015 -
Study of Ebola survivors opens in Liberia: Trial to examine long-term health effects of Ebola virus disease
NIAID/NIH news, June 17, 2015 -
Experimental Ebola vaccine safe, prompts immune response: Results from US government-sponsored phase 1 trial of VSV vaccine reported
NIAID/NIH news, April 1, 2015 -
Ebola test vaccines appear safe in Phase 2 Liberian clinical trial: Liberia-US partnership planning Phase 3 trial and study of Ebola survivors
NIAID/NIH news, March 26, 2015 - Recorded webcast:
Ebola Vaccines, Passive Immunotherapy, and Antiviral Treatment
presented by Dr H. Clifford Lane, NIAID
as a part of the Special Session: Ebola Virus Disease: Responding to the Challenge
at the February 2015
Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, WA -
Liberia-U.S. clinical research partnership opens trial to test Ebola treatments: Initial study will evaluate experimental drug cocktail ZMapp
NIAID/NIH news, February 27, 2015 -
Ethics and Ebola: Public Health Planning and Response [Archive]
Archive of the Presidential Commission for the Study of Bioethical Issues, released February 26, 2015 -
NIH Ebola vaccine trial gets underway in Liberia
Jan/Feb 2015
Global Health Matters -
Medical Education Partnership Initiative aids Ebola response
Jan/Feb 2015
Global Health Matters -
Ebola research funding initiative
from Wellcome Trust -
Cluster of Ebola virus disease linked to a single funeral - Moyamba District, Sierra Leone, 2014
Co-authored by Fogarty Deputy Director Dr. Peter H. Kilmarx
CDC
Morbidity and Mortality Weekly Report (MMWR), March 4, 2016 -
Scientists report on trial of early-generation Ebola, Marburg vaccine candidates: NIH-sponsored trial in Uganda informed development of current NIAID/GSK vaccine candidate
NIAID/NIH news, December 23, 2014 -
Building the human capacity to deal with Ebola: How can we prevent future disease outbreaks?
by Fogarty Director Dr Roger I Glass
American Society for Microbiology's
Cultures, Autumn 2014 -
NCATS repurposing test identifies 53 drugs that may block Ebola infection
NCATS/NIH news, December 2014 -
Obama visits NIH to call for more funding for Ebola research
Nov/Dec 2014
Global Health Matters -
NIH accelerates clinical trials of Ebola vaccines
Nov/Dec 2014
Global Health Matters -
Building the human capacity to deal with Ebola: How can we prevent future disease outbreaks?
Opinion by Fogarty Director Dr Roger I Glass
Nov/Dec 2014
Global Health Matters -
Lessons learned from 1976 Ebola outbreak:
Q and A with Fogarty Scientist Emeritus Dr Joel Breman
Nov/Dec 2014
Global Health Matters -
NIH special grand rounds on Ebola [Video]
Featuring NIAID Director Dr. Anthony S. Fauci and NIH Clinical Center colleagues
October 22, 2014 -
Transmission dynamics and control of Ebola virus disease outbreak in Nigeria, July to September 2014, co-authored by Fogarty staff scientist
Eurosurveillance, October 9, 2014 - Journal article:
Ebola then and now
coauthored by Fogarty Senior Scientific Adviser Emeritus Dr. Joel Breman
New England Journal of Medicine, Online First, September 10, 2014 -
Ebola outbreak strains sequenced
The Scientist, August 28, 2014 -
Eradicating Ebola: In U.S. biomedical research, we trust
NIH Director's Blog, August 11, 2014 -
Ebola outbreak highlights global disparities in healthcare resources
NIAID news, August 13, 2014 -
Recent Ebola outbreak highlights need for better global response
NIAID news, May 7, 2014
From the NIH research archives:
Other US Government Resources
- U.S. Centers for Disease Control and Prevention (CDC) Ebola resources:
- United States Agency for International Development (USAID):
Other Online Resources