Malaria Information and Resources

Malaria is a mosquito-borne disease causing fever, chills and flu-like illness that can be fatal. Despite an increased focus on malaria, it still claims hundreds of thousands of lives each year, most of them children in Africa. Poor quality antimalarial drugs, which lead to drug resistance and inadequate treatment, are also a growing concern, posing an urgent threat to vulnerable populations.

Fogarty has supported a wide range of efforts to combat malaria, including the Multilateral Initiative on Malaria, an international effort to identify and address malaria research priorities. Ecology and Evolution of Infectious Diseases, a joint NIH - National Science Foundation (NSF) initiative, funds malaria-related projects in Kenya, Papua New Guinea, Belize and more. Through the Global Infectious Disease program, Fogarty has supported research training efforts that advance scientific discoveries, while developing local malaria research capacity in places where it's needed most.

Fogarty's epidemiology division studies malaria transmission patterns, drug resistance and other related topics, modeling malaria's prevalence and impact.

Top News

• Tagging essential malaria genes to advance drug development
  Blog post by NIH Director Dr. Francis S. Collins, May 15, 2018
• Newly described human antibody prevents malaria in mice
  NIAID/NIH news, March 19, 2018
• NIH study identifies new targets for anti-malaria drugs
  NICHD/NIH news, October 26, 2017
• Eleventh Annual Report to Congress
   President’s Malaria Initiative (PMI), April 2017
• NIH statement on World Malaria Day
  NIAID/NIH news, April 25, 2017
• NIH funds seven International Centers of Excellence for Malaria Research that work in 14 countries in Africa, Asia and Latin America
  NIAID/NIH news, April 21, 2017
• NIH begins study of vaccine to protect against mosquito-borne diseases
  NIAID/NIH news, February 21, 2017
• Experimental PfSPZ malaria vaccine provides durable protection against multiple strains in NIH clinical trial
  NIAID/NIH news, February 21, 2017
• Related publication: PfSPZ vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection
  PNAS, February 21, 2017 (online)
• Investigational PfSPZ malaria vaccine demonstrates considerable protection in Malian adults for duration of malaria season
  NIAID/NIH news, February 16, 2017
• Related publication: Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial
  The Lancet Infectious Diseases, February 15, 2017 (online)
• Raising the curtain on cerebral malaria's deadly agents
  NINDS/NIH news, December 6, 2016
• Investigational malaria vaccine protects healthy U.S. adults for more than one year
  NIAID/NIH news, May 9, 2016
• A Big 'Woo-Hoo' for Europe on World Malaria Day: No New Cases in 2015 featuring Fogarty Senior Scientist Emeritus Dr Joel Breman
  NPR Goats and Soda blog, April 25, 2016
• Testing curbs malaria drug misuse in Kenya
  Jan / Feb 2016 Global Health Matters

• Chinese researchers discovered effectiveness of artemisinin against malaria
  Sep / Oct 2015 Global Health Matters
• Music video by NIH trainees in Cameroon urges malaria prevention
  Jul / Aug 2015 Global Health Matters
• Global pandemic of fake medicines poses urgent risk, scientists say
  May / Jun 2015 Global Health Matters
• Related publications: The Global Pandemic of Falsified Medicines: Laboratory and Field Innovations and Policy Perspectives
  June 2015 supplement to the American Journal of Tropical Medicine and Hygiene, published online April 20, 2015
• Stemming the tide of fake medicines
  New York Times editorial, May 18, 2015
• Why researchers say fake and low-quality drugs are a 'global pandemic'
  Washington Post, April 20, 2015
• Substandard drugs, not fakes, undermine fight against malaria
  Reuters Health, April 20, 2015
• Fake medicines do real damage: Thousands die, superbugs get stronger according to Fogarty Senior Scientist Emeritus Dr Joel Breman
  NPR Goats and Soda blog, April 24, 2015
• Fogarty Global Infectious Diseases grantee news: Malaria vaccine candidate produced from algae
  UC San Diego News, February 18, 2015
• Related publication: Algae-produced malaria transmission-blocking vaccine candidate Pfs25 formulated with a human use-compatible potent adjuvant induces high affinity antibodies that block Plasmodium falciparum infection of mosquitoes
  Infection and Immunity from the American Society for Microbiology (ASM), February 17, 2015 (online
• Q and A with world-renowned malaria research expert Dr Chris Plowe
  May / Jun 2015 Global Health Matters
• Fogarty Global Infectious Diseases grantee news:
  An American doctor may have solved a deadly mystery about malaria
  PRI's The World, May 5, 2015
• Study shows parasite mutation behind drug-resistant malaria in Cambodia
  Jan / Feb 2014 Global Health Matters
• WHO urges artemisinin resistance testing
  Jan / Feb 2014 Global Health Matters
• Fogarty funding spurs global health innovations, including a project to develop low-cost malaria diagnostics in Zambia
  Nov / Dec 2013 Global Health Matters
• Fogarty funds ecology, genetics studies of malaria in Ghana
  Nov / Dec 2013 Global Health Matters
• Malaria vaccine is safe, effective
  Sep / Oct 2013 Global Health Matters
• Investigational Malaria Vaccine Found Safe and Protective: NIH Vaccine Researchers Publish Results of Early-Stage Clinical Trial
  NIH / NIAID news release, August 8, 2013
• Fogarty grantee news: African Fever Patients Commonly Over-diagnosed With Malaria
  Duke Global Health Institute News, July 18, 2013
• FDA acts against compromised antimalarial drugs
  May / Jun 2013 Global Health Matters
• NIH partners with FDA: FDA launches partnership to protect against counterfeit anti-malarial medicines with FDA-developed handheld detection tool
  FDA News, April 24, 2013
• Fogarty grantee news: Researchers at University of Maryland School of Medicine to conduct malaria research and training in Burma - December 17, 2012
• Resistance to malaria drugs is a growing concern
  Sep / Oct 2012 Global Health Matters
• Related publication: Counterfeit antimalarial drugs
  The Lancet Infectious Diseases, November 2012
• Meeting Report on Fogarty and NIAID conference on artemisinin-resistant malaria: Artemisinin-Resistant Malaria: Research Challenges, Opportunities, and Public Health Implications, American Society of Tropical Medicine and Hygiene, August 2012
• Fogarty study shows poor quality and fake malaria drugs pose threat
  May / Jun 2012 Global Health Matters
• NIH study shows poor quality malaria drugs pose threat, Drug resistance a growing concern in Southeast Asia and sub-Saharan Africa
  NIH News, May 21, 2012
• Call to action on drug-resistant malaria
  Fogarty/NIH News, September 22, 2011
• Something new under the sea: promising malaria treatment found in Fiji
  Mar / Apr 2011 Global Health Matters
• Research in viral diseases aims at ending malaria
  Jan / Feb 2011 Global Health Matters
• Artesunate suppositories are economical, effective for malaria treatment
  Nov / Dec 2010 Global Health Matters
• Studying malaria and bioethics in Mali
  Jul / Aug 2010 Global Health Matters
• Deadly malaria parasite came from chimps
  Sep / Oct 2009 Global Health Matters
• Cognitive Deficits Linked to Cerebral Malaria in Children
  May / Jun 2008 Global Health Matters
• Deforestation impacts spread of infectious diseases in Peruvian Amazon
  Mar / Apr 2008 Global Health Matters
• Jan / Feb 2008 Global Health Matters focus on malaria:
• Genetically Engineered Mosquitoes May Aid in the Fight Against Malaria
• Latest Malaria Research Published in Supplement Edited by Fogarty Scientist
• Scientists Report that Misdiagnosis of Malaria is Common
• DDT's Ongoing Role in Malaria Control Examined
• Low-Cost Synthetic Form of Artemisinin May Provide Solution in Malaria Battle
• Top Malaria Experts Publish Groundbreaking Research to Aid Malaria Eradication
  Fogarty/NIH News, January 7, 2008

• Researchers Identify Genetic Marker of Resistance to Key Malaria Drug
  National Institute of Allergy and Infectious Diseases (NIAID) news, December 18, 2013
• Related publication information:
  PubMed info on A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
  Nature (online), December 18, 2013
• New door opens in the effort to stave off mosquito-borne diseases
  NIGMS Biomedical Beat blog, August 16, 2013
• HIV treatment reduces risk of malaria recurrence in children
  NIH News, November 28, 2012
• NIH supported research on Using Cell Phone Data to Curb the Spread of Malaria
  Harvard School of Public Health News, October 11, 2012
• National Institute of Allergy and Infectious Diseases (NIAID)
• NIAID Malaria Topic Page
• NIAID-funded centers seek to enhance malaria control
  Jul / Aug 2011 Global Health Matters
• Basis for key parasite function in malaria found
  Jul / Aug 2011 Global Health Matters
• National Library of Medicine (NLM)
• MedlinePlus on Malaria
• Malaria prevention goes online
  Jan / Feb 2009 Global Health Matters

• President's Malaria Initiative (PMI)
• Launch of PMI strategy 2015-2020
  from the President's Malaria Initiative, February 25, 2015
• Eleventh Annual Report to Congress
   President’s Malaria Initiative (PMI), April 2017
• Centers for Disease Control and Prevention (CDC) Malaria Topic Page
• Food and Drug Administration
• FDA launches partnership to protect against counterfeit anti-malarial medicines with FDA-developed handheld detection tool
  FDA news release, April 24, 2013
• Related publication: Evaluation of a New Handheld Instrument for the Detection of Counterfeit Artesunate by Visual Fluorescence Comparison
  American Journal of Tropical Medicine and Hygiene (online), September 29, 2014
• Department of Defense
• Army Researchers Continue Fight Against Malaria
  Department of Defense News, April 16, 2010
• Navy Researchers Work on Malaria Vaccine
  Department of Defense News, August 31, 2009
• U.S. Agency for International Development (USAID) on Fighting Malaria

• Malaria Foundation International
• PATH Malaria Vaccine Initiative
• Population Services International - Malaria Information
• Roll Back Malaria Partnership (RBM)
• World Malaria Day
• Together Against Malaria
• World Health Organization on Malaria
• WHO World Malaria Report 2016