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Defining the biology of HIV-associated aggressive B-cell lymphoma in Southern Africa

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

Emerging Global Leader

Project Information in NIH RePORTER

Defining the biology of HIV-associated aggressive B-cell lymphoma in Southern Africa

Principal Institution

Unversity of Cape Town

Principal Investigator(s) (PI)

Antel, Katherine

Project Contact Information

Email: katherineantel@gmail.com

Year(s) Awarded

2021-2026

Country

South Africa

NIH Partners

FIC, NCI

Project Description

Lymphoma is the leading cancer-cause of mortality in HIV, and diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma. The genetic landscape of HIV-associated DLBCL has not been well characterized. This project will genetically and transcriptionally define subtypes of HIV-associated DLBCL and correlate this with clinicopathologic features, in order to advance the development of low-cost molecular diagnostics for the region.

Related World Regions / Countries

Related Global Health Research Topics