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Innovations in Molecular Diagnostic Approaches for HIV-associated Lymphomas

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

HIV-associated Noncommunicable Diseases Research at LMIC Institutions

Project Information in NIH RePORTER

Innovations in Molecular Diagnostic Approaches for HIV-associated Lymphomas

Principal Institution

University of North Carolina Chapel Hill

Principal Investigator(s) (PI)

Fedoriw, Yuri

Project Contact Information

Email: yuri.fedoriw@unchealth.unc.edu

Year(s) Awarded

2025-2027

Country

Malawi

Project Description

As anti-retroviral therapy has become more widely available, a greater proportion of people with HIV globally, and in Southern Africa specifically, die from non-communicable diseases, especially aggressive B-cell lymphomas. However, diagnostic tools necessary to classify lymphomas to guide appropriate and available therapies are not widely accessible. Leveraging unique clinical and laboratory expertise, we will adapt low-cost nanopore sequencing and apply machine learning methods to enable cost-effective genomic diagnosis of HIV associated lymphomas in Malawi.

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