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Fidelity and Adaptation of Breast Cancer Resource-stratified Treatment Guidelines in Botswana

The following grant was awarded by, is supported by, is administered by or is in partnership with the Fogarty International Center at the U.S. National Institutes of Health (NIH).

Funding Fogarty Program

International Research Scientist Development Award (IRSDA)

Project Information in NIH RePORTER

Fidelity and Adaptation of Breast Cancer Resource-stratified Treatment Guidelines in Botswana

Principal Institution

University of Pennsylvania

Principal Investigator(s) (PI)

Martei, Yehoda Marteki

Project Contact Information

Email: yehoda.martei@uphs.upenn.edu

Year(s) Awarded

2020-2024

Country

Botswana

Collaborators

National Cancer Institute Center for Global health

NIH Partners

NCI

Project Description

Breast cancer burden is increasing in low- and middle- income countries, with a disproportionate burden of mortality in Sub Saharan Africa (SSA) and among HIV-infected patients. Although resource-stratified guidelines are cost-effective and lifesaving critical data is lacking on the implementation outcomes (e.g. treatment fidelity) of these guidelines. Understanding treatment fidelity and modifiers of fidelity, is necessary for 1) appropriate adaptation of resource-stratified guidelines to fit the context in which care is being delivered; and 2) design of interventions that maximize treatment fidelity and minimize random variability, in order to achieve targeted survival outcomes.

Related World Regions / Countries

Related Global Health Research Topics